Teaching CSIR NET Mock Test Series Life Sciences Cell Communication and Cell Signaling Immune System
One hundred IgM + B cells were plated at 1 cell/well and activated in vitro. This led to detectable proliferation in all wells by day four. At the end of seven days, it was found that some wells contained IgG1 antibodies, some contained both IgG1 and IgA antibodies, and some contained only IgA antibodies. The following interpretations were made:
A. Cells that have switched to IgG1 may undergo further switching to IgA.
B. Cells that have switched to IgA may undergo further switching to IgG1.
C. A single cell can simultaneously secrete IgG1 and IgA.
D. The progeny of proliferating cells may undergo independent switching events.
Which one of the following options represents the combination of all correct statements?
1
A and D
2
B and C
3
A and B
4
C and D