In eukaryotic cells, DNA replication is restricted to the S phase of the cell cycle because

1
DNA polymerase is present only in the S phase of the cell cycle.
2
Origin recognition complex (ORC) recognizes origin only in the S phase.
3
MCM helicases get activated in the S phase of the cell cycle.
4
MCM helicases get activated in the G1 phase of the cell cycle.

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