When E. coli and macrophages are placed in a petri dish with medium, the macrophages internalize the E. coli into cytoplasmic vesicles called phagosomes, which then fuse with lysosomes where the bacteria are killed. If E. coli is replaced by M. tuberculosis in the petri dish, which ONE of the following options will happen after attachment of the bacteria?
1
The bacteria will be internalized by pinocytosis.
2
The bacteria will be internalized by autophagy.
3
The bacteria will prevent the maturation of phagosomes.
4
The bacteria will prevent the generation of lysosomes in macrophages.