If the tails of mice are removed by surgery in each generation, do these tailless mice have tailless progeny?

1
Yes, there will be change in sex chromosomes
2
No, because removal of the tail cannot change the genes of the germ cells of the mice.
3
The length of the tail reduces with each generation and eventually gets lost.
4
Yes, because removal of the tail can change the genes of the germ cells of the mice

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