To evaluate insulin-dependent diabetes, clinicians prefer evaluating mono-glycated hemoglobin, referred to as HbA1c, which occurs due to a nonenzymatic reaction between glucose and a few amino acids in hemoglobin. Which of the following amino acids are likely to be involved in the modification of hemoglobin?
1
Asparagine and Glutamic acid
2
Proline and Tryptophan
3
Glutamine and Aspartic acid
4
Valine and Lysine