There are number of specific T cell surface molecules involved in various functions of adaptive immune response. Column X represents a list of T cell surface molecules and Column Y with the possible functional characteristics:

Column X

Column Y

A.

T cell receptor

(i)

binds to CD40 on B cells and APCs and triggers activation of APCs and activation/differentiation of B cells.

B.

CD28

(ii)

binds to MHC class I molecules and restricts I cytotoxic cells to recognizing only peptide presented on MHC class I

C.

CD8

(iii)

binds to B7 - 1, 2 or CD80/86 on B cells and APCs, which triggers T cell activation.

D.

CD154

(iv)

consists of two poly-peptide chains α and β and some consist of poly-peptide chains γ and δ.


Which of the following option has all correct matches?

1
A - (i); B - (ii); C - (iii); D - (iv)
2
A - (iv); B - (i); C - (ii); D - (iii)
3
A - (iii); B - (iv); C - (i); D - (ii)
4
A - (iv); B - (iii); C - (ii); D - (i)

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