What would be the effect of retinoic acid (RA) treatment on the ‘positional information’ of blastema cells present on the amputated newt limb?
1
RA will have no effect.
2
The cells will become respecified to more proximal position.
3
The cells will become respecified to more distal position.
4
Cells will lose their positional information and remain as dedifferentiated cells