Thermodynamics of protein folding is depicted as a free energy funnel below:

Given below are regions in the diagram (Column X) and their representation (Column Y)

X

Y

A.

(i)

Native structure

B.

(ii)

Structure with highest entropy

C.

(iii)

Molten globule

D.

(iv)

Discrete folding intermediates


Choose the option that shows all correct matches

1
A - (ii); B - (iii); C - (iv); D - (i)
2
A - (i); B - (ii); C - (iii); D - (iv)
3
A - (iii); B - (iv); C - (iii); D - (i)
4
A - (iv); B - (i); C - (ii); D - (iii)

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