Which of the following statements about site-specific recombinases is NOT true?

1
The Cre recombinase is believed to mediate the circularization of the Pl phage genome during infection of the bacterial host.
2
The λ integrase cannot mediate integration of the λ genome into the host genome without the help of accessory proteins.
3
The Hin invertase-mediated recombination event is stimulated by protein- DNA interactions at a 60 bp enhancer sequence.
4
In Xer recombinase-mediated monomerization of chromosomal dimers, the interaction of FtsK with XerCD activates XerC and initiates the re- combination process.

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