Teaching MPPSC Assistant Professor Mock Test Series 2025 Life Sciences Fundamental Processes DNA replication, repair and recombination
Which one of the following statements about Cre‐mediated site‐specific recombination at loxP sites is INCORRECT?
1
When loxP sites flanking a test sequence are oriented in same direction, Cre mediates the excision of the intervening sequence
2
LoxP sites in inverted orientation around an intervening sequence lead to inversion upon action by Cre recombinase
3
LoxP sites recognized by the Cre recombinase are palindromic around a spacer sequence
4
LoxP‐Cre system cannot be used to generate translocation between chromosomes.