What is the significance of the desmosine cross-link in elastin?

1
It degrades elastin and decreases its elasticity.
2
It acts as an intermolecular bridge that connects polypeptide chains.
3
It enhances the solubility of elastin in the extracellular matrix.
4
It is a unique tetrafunctional cross-link that contributes to the stability and elasticity of elastin fibers

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