If immunoglobulin purified from the polyclonal antiserum against BSA is digested with either pepsin or papain then it splits into fragments. Select the correct option.

1
Pepsin-digested fragments cannot precipitate the antigen
2
Papain-digested fragments cannot precipitate the antigen
3
Pepsin digestion will produce two Fab fragments joined by disulfide bonds
4
Papain digestion will remove disulfide bonds and produce one Fc fragment

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