During many important cell processes, many proteins need to undergo degradation to culminate a part of the process. For example, during cell cycle, cycling proteins need to be degraded to allow the cells to exit mitosis. This is achieved by selective ubiquitination of cyclin followed by its degradation by proteasomes. The specific protein factor that is involved in this process is called Anaphase Promoting Complex (APC). APC is possibly a protein which is known as

1
E1 enzyme.
2
E2 enzyme.
3
E3 enzyme.
4
Protease.

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