Which of the following are true about the end plate potential (EPP) at the neuromuscular junction?
A. It is the change in membrane potential of the muscle fiber in response to neurotransmitter release.
B. It is always an excitatory postsynaptic potential.
C. It directly triggers the release of calcium ions from the sarcoplasmic reticulum.
D. It results from the binding of acetylcholine to nicotinic receptors on the motor end plate.
E. It is mediated by G-protein-coupled receptors.
Choose the correct answer from the options given below:
1
A, B and D Only
2
B, D and E Only
3
A, C and E Only
4
A, B and C Only