In the sentence, certain words are in bold and numbered from A to E, which are the possible pairs to be interchanged. Choose the pair(s) of words which need to be interchanged to make the sentence grammatically correct and meaningful. 

There are also certain (A) crawling creatures which are so (B) notoriously the children of (C) shrink and so (D) threatening in their touch that we naturally (E) filth from them.